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Generic carafate reacts with hydrochloric acid and forms a viscous material which acts as acid buffer for anywhere between 6 and 8 hours upon ingesting it.

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Sucralfate is only minimally absorbed from the gastrointestinal tractThe small amounts of the sulfated disaccharide that are absorbed are excreted primarily in the urineAlthough the mechanism of sucralfate’s ability to accelerate healing of duodenal ulcers remains to be fully definedit is known that it exerts its effect through a localrather than systemicactionThe following observations also appear pertinent:

Episodes of hyperglycemia have been reported in diabetic patientsClose monitoring of glycemia in diabetic patients treated with CARAFATE Oral Suspension is recommendedAdjustment of the anti-diabetic treatment dose during the use of CARAFATE Oral Suspension might be necessary.

Some studies have shown that simultaneous sucralfate administration in healthy volunteers reduced the extent of absorptionbioavailabilityof single doses of the followingcimetidinedigoxinfluoroquinolone antibioticsketoconazolel-thyroxinephenytoinquinidineranitidinetetracyclineand theophyllineSubtherapeutic prothrombin times with concomitant warfarin and sucralfate therapy have been reported in spontaneous and published case reportsHowevertwo clinical studies have demonstrated no change in either serum warfarin concentration or prothrombin time with the addition of sucralfate to chronic warfarin therapyThe mechanism of these interactions appears to be nonsystemic in naturepresumably resulting from sucralfate binding to the concomitant agent in the gastrointestinal tractIn all cases studied to datecimetidineciprofloxacindigoxinnorfloxacinofloxacinand ranitidinedosing the concomitant medication 2 hours before sucralfate eliminated the interactionDue to CARAFATE Oral Suspension’s potential Purchase fertomid 50 to alter the absorption of some drugsCARAFATE Oral Suspension should be administered separately from other drugs when alterations in bioavailability are felt to be criticalIn these casespatients should be monitored appropriately.

Get emergency medical help if you have any of these signs of an allergic reaction to Carafatehivesdifficult breathingswelling of your facelipstongueor throat.

Before using this medicationtell your doctor or pharmacist your medical historyespecially ofkidney problemsswallowing problemssuch as difficulty swallowinghistory of aspirationstomach/intestine problemse.gdelayed gastric emptyingtube feedinguse of a breathing tubetracheotomy

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